Anti- VEGF: A Possible Mainstream Treatment for Retinopathy of Prematurity

When a child is born before two months or more, there is an augmented chance they will have a condition called retinopathy of prematurity, characterized by the development of irregular blood vessels in the retina of the fetus. Although numerous cases of ROP are mild, with very little influence on vision, there are more aggressive cases resulting in eye damage or even loss of sight.


What Is ROP?

The retina lines the hind portion of the eye, where it captures info in form of light and sending it to the brain, which systematizes and translates the info into an image. When in the womb, eyes of the baby start developing between the 5th and 8th months of gestation, ultimately leading to the complete formation of the retina, and all the other parts of the eye. The fetal retina starts to grow blood vessels at around the 16th week of pregnancy and will endure to grow throughout the pregnancy.

What It Means for My Child

Numerous children with ROP have mild impact and will see usually. Though, premature babies, severely underweight are the most susceptible to developing an advanced ROP. Also, if the disorder is severe, it may become further serious. Signs of an infant having severe ROP include:

• White scarring or pupil discoloration 

• Involuntary movements of the eye

• Incapability to retort to light properly

Diagnosis of ROP

Premature babies are sent to the hospital’s NICU where they testing is done to quantify their health. This includes an eye examination for if there are any retinal problems. The ophthalmologist will dilate the pupil of the baby to have a better look at the retina. Digital imaging might also be used to capture retina images to be analyzed by a specialist.

Recently, doctors have started using anti-vascular endothelial growth factor anti-VEGF injections such as Avastin and Lucentis for disrupting the growth of abnormal blood vessels. Though anti-VEGF medications are standard of care for numerous retinal conditions like wet age-related macular degeneration and proliferative diabetic retinopathy, research is still going on regarding this treatment being suitable for ROP.

The anti-VEGF treatment being the common treatment for most of the eye issues, and there can be chances of it being the mainstream treatment for ROP, the demand for the sane will be on the rise. That’s why the value of the same will reach about $13,813 million in 2030.

Access Detailed Report - Anti-VEGF Therapeutics Market Growth Forecast Report


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